The replacement of neonicotinoid insecticides-sulfoxaflor

Sulfoxaflor developed the first novel sulfonimide agricultural pesticide for Dow AgroSciences in the United States. At the World Pesticide Research Conference held in London, UK on November 2, 2010. The insecticidal spectrum of sulfoxaflor is different from that of neonicotinoid insecticides. It also has a higher control effect on piercing insects that are resistant to neonicotinoids. It can be said to be one of the resistance management aspects.

The new control agent was recognized as the only member of the new Group 4C pesticide by the Insecticide Resistance Action Committee.The molecular formula of sulfoxaflor is C10H10F3N3OS, and the chemical structure is as follows:

Mechanism of action
It acts on the unique binding site of the acetylcholine receptor of the sucker pests and exerts its insecticidal effect. The action mode of sulfoxaflor is contact killing and stomach poisoning. It has systemic conduction and osmotic effects. It has high efficiency and broad-spectrum activity.
Low and long residual period.
It is suitable for controlling aphids, whiteflies, planthoppers and scale insects.
It can effectively control piercing and sucking mouthparts pests that are resistant to nicotine, pyrethroid, organophosphorus and carbamate pesticides.
Low toxicity to non-target arthropods.
Target pests
Sulfoxaflor has a broad spectrum of action. It can be used for cotton, rape, fruit trees, soybeans, fruits, small grains, vegetables, rice, lawns and ornamental plants to control aphids, bugs, bugs, whiteflies, scale insects, fly
Lice, certain psyllids, thrips and many other piercing and sucking pests.
No cross-resistance with other pesticides.
Toxicity
Acute oral LD50 of the original drug: 1 000 mg/kg in female rats and 1 405 mg/kg in male rats; Acute dermal LD50 of the original drug: rats (female/male)> 5 000 mg/kg.
Acute oral LD50 of preparation: ＞2 000 mg/kg

Patent status :

Patent name: Insecticidal N-Substituted (6-haloalkylpyridin-3-yl-)alkyl Sulfoximines. Patent No.: WO2007095229, Patent Publication Date: 2007-8-23. Patent application date: 2007-2-9. Patent priority date: 2006-2-10; 2006-8-7. Patent owner: DOW AGROSCIENCES LLC. The expiration date of the patent for sulfoxaflor is 2026.